Article
A polymorphism in miR-1262 regulatory region confers the risk of lung cancer in Chinese population.
International journal of cancer - 1 Sept 2017
Xie Kaipeng, Chen Mengxi, Zhu Meng, Wang Cheng, Qin Na, Liang Cheng, Song Ci, Dai Juncheng, Jin Guangfu, Shen Hongbing, Lin Dongxin, Ma Hongxia, Hu Zhibin
Abstract excerpt
It has been proposed that the majority of disease-associated loci identified by genome-wide association studies (GWAS) are enriched in non-coding regions, such as the promoter, enhancer or non-coding RNA genes. Thus, we performed a two-stage case-control study to systematically evaluate the association of genetic variants in miRNA regulatory regions (promoter and enhancer) with lung cancer risk in 7,763 subjects...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.