Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Statin modulation of monocyte phenotype and function: implications for HIV-1-associated neurocognitive disorders.

Journal of neurovirology - 1 Oct 2016

Yadav Anjana, Betts Michael R, Collman Ronald G

Abstract excerpt

HIV-1-associated neurocognitive disorder (HAND) remains a persistent problem despite antiretroviral therapy (ART), largely a result of continued inflammation in the periphery and the brain and neurotoxin release from activated myeloid cells in the CNS. CD14+CD16+ inflammatory monocytes, expanded in HIV infection, play a central role in the pathogenesis of HAND and have parallels with monocyte-dependent...

Topics

Join the communities discussing this publication.

AIDS Dementia Complex
Antigens, Differentiation, Myelomonocytic
Atorvastatin
CD163 Antigen
Chemokine CCL3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Healthy Volunteers

Primary Cell Culture

Source

Open in PubMed Open full text

Identifiers

PMID: 27021071
DOI: 10.1007/s13365-016-0433-8
PMCID: PMC5040617

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Statin modulation of monocyte phenotype and function: implications for HIV-1-associated neurocognitive disorders.PMID 27021071Read ↗

Single-cell analysis of CD14+CD16+ monocytes identifies a subpopulation with an enhanced migratory and inflammatory phenotype.Semantic proximity Read ↗

A Sex-Stratified Analysis of Monocyte Phenotypes Associated with HIV Infection in Uganda.Semantic proximity Read ↗

JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individualsSemantic proximity Read ↗

Monocyte/macrophages and their role in HIV neuropathogenesis.Semantic proximity Read ↗

Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System.Semantic proximity Read ↗

Persistent Inflammation and Non-AIDS Comorbidities During ART: Coming of the Age of MonocytesSemantic proximity Read ↗

Clinical significance of monocyte heterogeneitySemantic proximity Read ↗

Role of non-classical monocytes in HIV-associated vascular cognitive impairmentSemantic proximity Read ↗

Cannabis use by people with HIV is associated with an anti-inflammatory immunometabolic phenotype in monocyte-derived macrophages.Semantic proximity Read ↗

Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy.Semantic proximity Read ↗

Central Nervous System Damage, Monocytes and Macrophages, and Neurological Disorders in AIDSSemantic proximity Read ↗

Brief Report: Peripheral Monocyte/Macrophage Phenotypes Associated With the Evolution of Cognitive Performance in HIV-Infected Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.