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Article

Genetic Variants of LDLR and PCSK9 Associated with Variations in Response to Antihypercholesterolemic Effects of Armolipid Plus with Berberine.

PloS one - 1 Jan 2016

De Castro-Orós Isabel, Solà Rosa, Valls Rosa María, Brea Angel, Mozas Pilar, Puzo Jose, Pocoví Miguel

Abstract excerpt

BACKGROUND: Armolipid Plus (AP) is a nutraceutical that contains policosanol, fermented rice with red yeast, berberine, coenzyme Q10, folic acid, and astaxanthin. It has been shown to be effective in reducing plasma LDL cholesterol (LDLc) levels. In the multicenter randomized trial NCT01562080, there was large interindividual variability in the plasma LDLc response to AP supplementation. We hypothesized that the...

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Source

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Identifiers

PMID: 27015087
DOI: 10.1371/journal.pone.0150785
PMCID: PMC4807809

Genes

LDLR
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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