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Article

FHSA-SED: Two-Locus Model Detection for Genome-Wide Association Study with Harmony Search Algorithm.

PloS one - 1 Jan 2016

Tuo Shouheng, Zhang Junying, Yuan Xiguo, Zhang Yuanyuan, Liu Zhaowen

Abstract excerpt

MOTIVATION: Two-locus model is a typical significant disease model to be identified in genome-wide association study (GWAS). Due to intensive computational burden and diversity of disease models, existing methods have drawbacks on low detection power, high computation cost, and preference for some types of disease models. METHOD: In this study, two scoring functions (Bayesian network based K2-score and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27014873
DOI: 10.1371/journal.pone.0150669
PMCID: PMC4807955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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