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Article

Extracting genetic alteration information for personalized cancer therapy from ClinicalTrials.gov.

Journal of the American Medical Informatics Association : JAMIA - 1 Jul 2016

Xu Jun, Lee Hee-Jin, Zeng Jia, Wu Yonghui, Zhang Yaoyun, Huang Liang-Chin, Johnson Amber, Holla Vijaykumar, Bailey Ann M, Cohen Trevor, Meric-Bernstam Funda, Bernstam Elmer V, Xu Hua

Abstract excerpt

OBJECTIVE: Clinical trials investigating drugs that target specific genetic alterations in tumors are important for promoting personalized cancer therapy. The goal of this project is to create a knowledge base of cancer treatment trials with annotations about genetic alterations from ClinicalTrials.gov. METHODS: We developed a semi-automatic framework that combines advanced text-processing techniques with manual...

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Identifiers

PMID: 27013523
DOI: 10.1093/jamia/ocw009
PMCID: PMC4926744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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