Article
Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jun 2016
Morrow C J, Trapani F, Metcalf R L, Bertolini G, Hodgkinson C L, Khandelwal G, Kelly P, Galvin M, Carter L, Simpson K L, Williamson S, Wirth C, Simms N, Frankliln L, Frese K K, Rothwell D G, Nonaka D, Miller C J, Brady G, Blackhall F H, Dive C
Abstract excerpt
BACKGROUND: Over the past decade, numerous reports describe the generation and increasing utility of non-small-cell lung cancer (NSCLC) patient-derived xenografts (PDX) from tissue biopsies. While PDX have proven useful for genetic profiling and preclinical drug testing, the requirement of a tissue biopsy limits the available patient population, particularly those with advanced oligometastatic disease....
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