Article
A prospective examination of circulating tumor cell profiles in non-small-cell lung cancer molecular subgroups.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jul 2017
Lindsay C R, Faugeroux V, Michiels S, Pailler E, Facchinetti F, Ou D, Bluthgen M V, Pannet C, Ngo-Camus M, Bescher G, Caramella C, Billiot F, Remon J, Planchard D, Soria J-C, Besse B, Farace F
Abstract excerpt
BACKGROUND: We report the first study examining the clinical, numerical and biological properties of circulating tumor cells according to molecular subtypes of non-small-cell lung cancer. PATIENTS AND METHODS: 125 patients with treatment-naïve stage IIIb-IV NSCLC were prospectively recruited for CellSearch analysis. Anti-vimentin antibody was included for examination of CTCs to assess their mesenchymal character....
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