Article
Association between Leptin G2548A and Leptin Receptor Q223R Polymorphisms with Type 2 Diabetes in an Iranian Population.
Clinical laboratory - 1 Jan 2016
Meshkani Reza, Nasimian Ahmad, Taheripak Gholamreza, Zarghooni Maryam, Rezaei Maryam, Sadeghi Asie, Eshkiki Zahra Shokati
Abstract excerpt
BACKGROUND: The leptin (LEP G2548A) and leptin receptor (LEPR Q223R) gene polymorphisms have been variably associated with type 2 diabetes (T2D) in different populations. In this study we hypothesized that these variants might be associated with T2D and related metabolic traits in an Iranian population. METHODS: The LEP G2548A and LEPR Q223R genotypes were determined by PCR-RFLP in 378 normoglycemic controls and...
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