Article
Analysis of Gln223Agr polymorphism of Leptin Receptor Gene in type II diabetic mellitus subjects among Malaysians.
International journal of molecular sciences - 18 Sept 2013
Etemad Ali, Ramachandran Vasudevan, Pishva Seyyed Reza, Heidari Farzad, Aziz Ahmad Fazli Abdul, Yusof Ahmad Khairuddin Mohamed, Pei Chong Pei, Ismail Patimah
Abstract excerpt
Leptin is known as the adipose peptide hormone. It plays an important role in the regulation of body fat and inhibits food intake by its action. Moreover, it is believed that leptin level deductions might be the cause of obesity and may play an important role in the development of Type 2 Diabetes Mellitus (T2DM), as well as in cardiovascular diseases (CVD). The Leptin Receptor (LEPR) gene and its polymorphisms...
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