Article
Genome wide association study identifies two loci associated with cadmium in erythrocytes among never-smokers.
Human molecular genetics - 1 Jun 2016
Borné Yan, Söderholm Martin, Barregard Lars, Fagerberg Björn, Persson Margaretha, Melander Olle, Thévenod Frank, Hedblad Bo, Engström Gunnar
Abstract excerpt
BACKGROUND: Cadmium is a non-essential toxic metal with multiple adverse health effects. Exposure in the general population occurs by smoking and diet. Cadmium in erythrocytes is a valid biomarker of exposure and body burden of cadmium. OBJECTIVES: We aimed to identify genetic variants related to concentrations of cadmium in erythrocytes. METHODS: Erythrocyte cadmium was analyzed in 4432 individuals (1728 never...
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