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Epidermal Growth Factor Receptor (EGFR) Gene Polymorphism May be a Modifier for Cadmium Kidney Toxicity.

Genes - 2 Oct 2021

Lin Chun-Ting, Chen Ting-Hao, Yang Chen-Cheng, Luo Kuei-Hau, Chen Tzu-Hua, Chuang Hung-Yi

Abstract excerpt

The results of many studies indicate that cadmium (Cd) exposure is harmful to humans, with the proximal tubule of the kidney being the main target of Cd accumulation and toxicity. Studies have also shown that Cd has the effect of activating the pathway of epidermal growth factor receptor (EGFR) signaling and cell growth. The EGFR is a family of transmembrane receptors, which are widely expressed in the human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34680968
DOI: 10.3390/genes12101573
PMCID: PMC8535213

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