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Article

RAS mutation is a prognostic biomarker in colorectal cancer patients with metastasectomy.

International journal of cancer - 15 Aug 2016

Osumi Hiroki, Shinozaki Eiji, Suenaga Mitsukuni, Matsusaka Satoshi, Konishi Tsuyoshi, Akiyoshi Takashi, Fujimoto Yoshiya, Nagayama Satoshi, Fukunaga Yosuke, Ueno Masashi, Mise Yoshihiro, Ishizawa Takeaki, Inoue Yosuke, Takahashi Yu, Saiura Akio, Uehara Hirohumi, Mun Mingyon, Okumura Sakae, Mizunuma Nobuyuki, Miki Yoshio, Yamaguchi Toshiharu

Abstract excerpt

Studies have demonstrated a relationship between clinical outcomes after curative resection for colorectal cancer (CRC) and gene mutations of the EGFR pathway; however, no studies have examined metastatic CRC (mCRC) patients with metastasectomy. The aim of this study was to evaluate the relationship between gene mutations of EGFR pathway and clinical outcomes after metastasectomy in mCRC patients. A total of...

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Source

Identifiers

PMID: 27004837
DOI: 10.1002/ijc.30106

Genes

EGFR
KRAS
BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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