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Article

Splice form variant and amino acid changes in MDR49 confers DDT resistance in transgenic Drosophila.

Scientific reports - 22 Mar 2016

Seong Keon Mook, Sun Weilin, Clark John M, Pittendrigh Barry R

Abstract excerpt

The ATP-binding cassette (ABC) transporters represent a superfamily of proteins that have important physiological roles in both prokaryotes and eukaryotes. In insects, ABC transporters have previously been implicated in insecticide resistance. The 91-R strain of Drosophila melanogaster has been intensely selected with DDT over six decades. A recent selective sweeps analysis of 91-R implicated the potential role...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27003579
DOI: 10.1038/srep23355
PMCID: PMC4802207

Genes

DDT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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