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Article

Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo.

The Journal of cell biology - 28 Mar 2016

Melchionda Manuela, Pittman Jon K, Mayor Roberto, Patel Sandip

Abstract excerpt

Increasing evidence implicates Ca(2+) in the control of cell migration. However, the underlying mechanisms are incompletely understood. Acidic Ca(2+) stores are fast emerging as signaling centers. But how Ca(2+) is taken up by these organelles in metazoans and the physiological relevance for migration is unclear. Here, we identify a vertebrate Ca(2+)/H(+)exchanger (CAX) as part of a widespread family of...

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Identifiers

PMID: 27002171
DOI: 10.1083/jcb.201510019
PMCID: PMC4810305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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