Article
Investigation of KIF6 Trp719Arg gene polymorphism in a case-control study of coronary artery disease and non-fatal myocardial infarction in the Eastern Province of Saudi Arabia.
Annals of Saudi medicine - 1 Jan 2000
Vatte Chittibabu, Cyrus Cyril, Al Shehri Abdullah Mohammed, Chathoth Shahanas, Almansori Mohammed, Al-Nafaie Awatif, Al-Ali Rudaynah, Al-Muhanna Fahad, Asselbergs Folkert W, Al-Ali Amein
Abstract excerpt
BACKGROUND: Kinesin-like protein 6 (KIF6), a member of the kinesin superfamily, is involved in intracellular transport. A few prospective studies have shown the KIF6 variant Trp719Arg (rs20455) to be associated with coronary artery disease (CAD) in Caucasian populations. However, recent genome-wide association studies on CAD have not proven these associations. OBJECTIVES: Since the role of KIF6 719Arg allele in...
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