Article
A single-nucleotide polymorphism in the MicroRNA-146a gene is associated with diabetic nephropathy and sight-threatening diabetic retinopathy in Caucasian patients.
Acta diabetologica - 1 Aug 2016
Kaidonis Georgia, Gillies Mark C, Abhary Sotoodeh, Liu Ebony, Essex Rohan W, Chang John H, Pal Bishwanath, Sivaprasad Sobha, Pefkianaki Maria, Daniell Mark, Lake Stewart, Petrovsky Nikolai, Hewitt Alex W, Jenkins Alicia, Lamoureux Ecosse L, Gleadle Jonathan M, Craig Jamie E, Burdon Kathryn P
Abstract excerpt
AIMS: This study aimed to investigate whether the single-nucleotide polymorphism (SNP) rs2910164 residing within microRNA-146a (miR-146a) is associated with diabetic microvascular complications diabetic nephropathy (DN), proliferative diabetic retinopathy (PDR) or diabetic macular oedema (DME) in either Caucasian patients with type 1 (T1DM) or type 2 (T2DM) diabetes mellitus. METHODS: Caucasian patients with T1DM...
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