Cluster-randomised non-inferiority trial comparing DVD-assisted and traditional genetic counselling in systematic population testing for BRCA1/2 mutations.

doi:10.1136/jmedgenet-2015-103740

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Article

Cluster-randomised non-inferiority trial comparing DVD-assisted and traditional genetic counselling in systematic population testing for BRCA1/2 mutations.

Journal of medical genetics - 1 Jul 2016

Manchanda Ranjit, Burnell Matthew, Loggenberg Kelly, Desai Rakshit, Wardle Jane, Sanderson Saskia C, Gessler Sue, Side Lucy, Balogun Nyala, Kumar Ajith, Dorkins Huw, Wallis Yvonne, Chapman Cyril, Tomlinson Ian, Taylor Rohan, Jacobs Chris, Legood Rosa, Raikou Maria, McGuire Alistair, Beller Uziel, Menon Usha, Jacobs Ian

Abstract excerpt

BACKGROUND: Newer approaches to genetic counselling are required for population-based testing. We compare traditional face-to-face genetic counselling with a DVD-assisted approach for population-based BRCA1/2 testing. METHODS: A cluster-randomised non-inferiority trial in the London Ashkenazi Jewish population. INCLUSION CRITERIA: Ashkenazi Jewish men/women >18 years; exclusion criteria: (a) known BRCA1/2...

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PMID: 26993268
DOI: 10.1136/jmedgenet-2015-103740

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BRCA1

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