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Article

Atypical femoral fracture in a 51-year-old woman: Revealing a hypophosphatasia.

Joint bone spine - 1 May 2016

Maman Esther, Briot Karine, Roux Christian

Abstract excerpt

We report a 51-year old woman who suffered 2 atypical subtrochanteric femoral fractures (AFFs). She had a history of several metatarsal fractures. She had a normal bone densitometry. An adult form of hypophosphatasia (HPP) was diagnosed from low serum alkaline phosphatase (ALP), and tissue nonspecific isoenzyme of ALP (TNSALP) mutation analysis revealing 2 heterozygous mutations: c.299C>T (p. T100M) and c.571G>A...

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PMID: 26992955
DOI: 10.1016/j.jbspin.2015.10.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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