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Article

Kinesin-1 inhibits the aggregation of amyloid-β peptide as detected by fluorescence cross-correlation spectroscopy.

FEBS letters - 1 Apr 2016

Zheng Yanpeng, Tian Shijun, Peng Xianglei, Yang Jingfa, Fu Yuanhui, Jiao Yueying, Zhao Jiang, He Jinsheng, Hong Tao

Abstract excerpt

Although the exact etiology and pathogenesis of Alzheimer's disease (AD) are still unclear, amyloid-β (Aβ) generated by the proteolytic processing of amyloid-β precursor protein (APP) aggregate to form toxic amyloid species. Kinesin-1 is the first identified ATP-dependent axonal transport motor protein that has been proven to affect Aβ generation and deposition. In this paper, we applied dual-color fluorescence...

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Source

Identifiers

PMID: 26991731
DOI: 10.1002/1873-3468.12137

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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