Article
Exploiting the Adaptation Dynamics to Predict the Distribution of Beneficial Fitness Effects.
PloS one - 1 Jan 2016
John Sona, Seetharaman Sarada
Abstract excerpt
Adaptation of asexual populations is driven by beneficial mutations and therefore the dynamics of this process, besides other factors, depends on the distribution of beneficial fitness effects. It is known that on uncorrelated fitness landscapes, this distribution can only be of three types: truncated, exponential and power law. We performed extensive stochastic simulations to study the adaptation dynamics on...
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