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Article

Is APOE ε4 associated with poorer cognitive outcome following traumatic brain injury? A meta-analysis.

Neuropsychology - 1 Oct 2016

Padgett Christine R, Summers Mathew J, Skilbeck Clive E

Abstract excerpt

OBJECTIVE: Cognitive impairment is a common sequelae of traumatic brain injury (TBI); however, predicting who will experience poorer outcomes remains challenging. A potential risk factor that has gained attention is the APOE gene, with the ε4 allele hypothesized to have a detrimental effect on post-TBI cognitive outcome. The aim of this meta-analysis was to evaluate the effect of APOE ε4 both in terms of general...

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Source

Identifiers

PMID: 26986748
DOI: 10.1037/neu0000270

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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