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Article

Influence of APOE polymorphism on cognitive and behavioural outcome in moderate and severe traumatic brain injury.

Journal of neurology, neurosurgery, and psychiatry - 1 Oct 2006

Ariza M, Pueyo R, Matarín M del M, Junqué C, Mataró M, Clemente I, Moral P, Poca M A, Garnacho A, Sahuquillo J

Abstract excerpt

AIM: To analyse the influence of apolipoprotein (APOE) epsilon4 status on the cognitive and behavioural functions usually impaired after moderate and severe traumatic brain injury (TBI). METHODS: In all, 77 patients with TBI selected from 140 consecutive admissions were genotyped for APOE. Each patient was subjected to neuropsychological and neurobehavioural assessment at least 6 months after injury. RESULTS:...

Topics

Apolipoprotein E4
Apolipoproteins E
Attention
Brain Injuries
Cognition
Cohort Studies
Frontal Lobe
Genotype
Humans
Motor Skills
Neuropsychological Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Severity of Illness Index

Temporal Lobe

Treatment Outcome

Visual Perception

Source

Open in PubMed Open full text

Identifiers

PMID: 16614010
DOI: 10.1136/jnnp.2005.085167
PMCID: PMC2077553

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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