Article
Apolipoprotein E epsilon 4 (APOE-ε4) genotype is associated with decreased 6-month verbal memory performance after mild traumatic brain injury.
Brain and behavior - 1 Sept 2017
Yue John K, Robinson Caitlin K, Burke John F, Winkler Ethan A, Deng Hansen, Cnossen Maryse C, Lingsma Hester F, Ferguson Adam R, McAllister Thomas W, Rosand Jonathan, Burchard Esteban G, Sorani Marco D, Sharma Sourabh, Nielson Jessica L, Satris Gabriela G, Talbott Jason F, Tarapore Phiroz E, Korley Frederick K, Wang Kevin K W, Yuh Esther L, Mukherjee Pratik, Diaz-Arrastia Ramon, Valadka Alex B, Okonkwo David O, Manley Geoffrey T
Abstract excerpt
INTRODUCTION: The apolipoprotein E (APOE) ε4 allele associates with memory impairment in neurodegenerative diseases. Its association with memory after mild traumatic brain injury (mTBI) is unclear. METHODS: mTBI patients (Glasgow Coma Scale score 13-15, no neurosurgical intervention, extracranial Abbreviated Injury Scale score ≤1) aged ≥18 years with APOE genotyping results were extracted from the Transforming...
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