Dissecting Epigenetic Dysregulation of Primary Antibody Deficiencies.

Abstract excerpt

Primary antibody deficiencies (PADs), the most prevalent inherited primary immunodeficiencies (PIDs), are associated with a wide range of genetic alterations (both monogenic or polygenic) in B cell-specific genes. However, correlations between the genotype and clinical manifestations are not evident in all cases indicating that genetic interactions, environmental and epigenetic factors may have a role in PAD...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Agammaglobulinemia
• Share to Antibody Affinity