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Systemic lupus erythematosus and immunodeficiency

1 Sept 2021

Abstract excerpt

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease caused by a combination of genetic, epigenetic, and environmental factors. Recent advances in genetic analysis coupled with better understanding of different immune regulatory and signaling pathways have revealed the complex relationship between autoimmunity, including SLE, and immunodeficiency. Furthermore, the expanding therapeutic...

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PMID: 36465072
DOI: 10.2478/rir-2021-0019

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