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Article

An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells

17 Mar 2016

Abstract excerpt

Radiotherapy is a mainstay of curative prostate cancer treatment, but risks of recurrence after treatment remain significant in locally advanced disease. Given that tumor relapse can be attributed to a population of cancer stem cells (CSC) that survives radiotherapy, analysis of this cell population might illuminate tactics to personalize treatment. However, this direction remains challenging given the plastic...

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PMID: 26984757
DOI: 10.1158/0008-5472.can-15-2116

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