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Article

The Angiotensin Converting Enzyme Insertion/Deletion Polymorphism Modifies Exercise-Induced Muscle Metabolism.

PloS one - 1 Jan 2016

Vaughan David, Brogioli Michael, Maier Thomas, White Andy, Waldron Sarah, Rittweger Jörn, Toigo Marco, Wettstein Jessica, Laczko Endre, Flück Martin

Abstract excerpt

OBJECTIVE: A silencer region (I-allele) within intron 16 of the gene for the regulator of vascular perfusion, angiotensin-converting enzyme (ACE), is implicated in phenotypic variation of aerobic fitness and the development of type II diabetes. We hypothesised that the reportedly lower aerobic performance in non-carriers compared to carriers of the ACE I-allele, i.e. ACE-DD vs. ACE-ID/ACE-II genotype, is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to INDEL Mutation

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Share to Peptidyl-Dipeptidase A

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Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 26982073
DOI: 10.1371/journal.pone.0149046
PMCID: PMC4794249

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Angiotensin Converting Enzyme Insertion/Deletion Polymorphism Modifies Exercise-Induced Muscle Metabolism.PMID 26982073Read ↗

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