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Article

Back to the tubule: microtubule dynamics in Parkinson's disease.

Cellular and molecular life sciences : CMLS - 1 Feb 2017

Pellegrini Laura, Wetzel Andrea, Grannó Simone, Heaton George, Harvey Kirsten

Abstract excerpt

Cytoskeletal homeostasis is essential for the development, survival and maintenance of an efficient nervous system. Microtubules are highly dynamic polymers important for neuronal growth, morphology, migration and polarity. In cooperation with several classes of binding proteins, microtubules regulate long-distance intracellular cargo trafficking along axons and dendrites. The importance of a delicate interplay...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27600680
DOI: 10.1007/s00018-016-2351-6
PMCID: PMC5241350

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