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Article

Heterogeneity of KRAS Mutations in Pancreatic Ductal Adenocarcinoma.

Pancreas - 1 Sept 2016

Hashimoto Daisuke, Arima Kota, Yokoyama Naomi, Chikamoto Akira, Taki Katsunobu, Inoue Risa, Kaida Takayoshi, Higashi Takaaki, Nitta Hidetoshi, Ohmuraya Masaki, Hirota Masahiko, Beppu Toru, Baba Hideo

Abstract excerpt

OBJECTIVES: Activating Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations are the most common and frequent changes observed in pancreatic cancer. This study aimed to determine the frequency and extent of intratumoral and metastatic lymph node KRAS mutation heterogeneity of resected pancreatic ductal adenocarcinoma. METHODS: Tumor tissues macrodissected from tumor centers, invasion fronts (n = 97), and...

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Share to Adenocarcinoma
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to KRAS gene

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Share to Pancreatic Neoplasms

Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 26967456
DOI: 10.1097/MPA.0000000000000624

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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