Article
Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD.
The European respiratory journal - 1 Jun 2016
Balgoma David, Yang Mingxing, Sjödin Marcus, Snowden Stuart, Karimi Reza, Levänen Bettina, Merikallio Heta, Kaarteenaho Riitta, Palmberg Lena, Larsson Kjell, Erle David J, Dahlén Sven-Erik, Dahlén Barbro, Sköld C Magnus, Wheelock Åsa M, Wheelock Craig E
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality; however, the role of inflammatory mediators in its pathobiology remains unclear. The aim of this study was to investigate the influence of gender in COPD on lipid mediator levels.Bronchoalveolar lavage fluid (BALF) and serum were obtained from healthy never-smokers, smokers and COPD patients (Global Initiative for Chronic Obstructive...
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