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Comprehensive annotations of human herpesvirus 6A and 6B genomes reveal novel and conserved genomic features

16 Jan 2020

Abstract excerpt

Human herpesvirus-6 (HHV-6) A and B are ubiquitous betaherpesviruses, infecting the majority of the human population. They encompass large genomes and our understanding of their protein coding potential is far from complete. Here, we employ ribosome-profiling and systematic transcript-analysis to experimentally define HHV-6 translation products. We identify hundreds of new open reading frames (ORFs), including...

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PMID: 31944176
DOI: 10.7554/elife.50960

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