Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Herpesvirus Genome Integration into Telomeric Repeats of Host Cell Chromosomes

8 Jul 2014

Abstract excerpt

It is well known that numerous viruses integrate their genetic material into host cell chromosomes. Human herpesvirus 6 (HHV-6) and oncogenic Marek's disease virus (MDV) have been shown to integrate their genomes into host telomeres of latently infected cells. This is unusual for herpesviruses as most maintain their genomes as circular episomes during the quiescent stage of infection. The genomic DNA of HHV-6,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26958721
DOI: 10.1146/annurev-virology-031413-085422

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Herpesvirus Genome Integration into Telomeric Repeats of Host Cell ChromosomesPMID 26958721Read ↗

Herpesvirus telomeric repeats facilitate genomic integration into host telomeres and mobilization of viral DNA during reactivation.Semantic proximity Read ↗

The Telomeric Repeats of Human Herpesvirus 6A (HHV-6A) Are Required for Efficient Virus IntegrationSemantic proximity Read ↗

Latency, Integration, and Reactivation of Human Herpesvirus-6Semantic proximity Read ↗

Herpesviruses and Chromosomal IntegrationSemantic proximity Read ↗

HHV-6A/B Integration and the Pathogenesis Associated with the Reactivation of Chromosomally Integrated HHV-6A/BSemantic proximity Read ↗

Telomeres and viruses: common themes of genome maintenanceSemantic proximity Read ↗

The molecular biology of human herpesvirus-6 latency and telomere integrationSemantic proximity Read ↗

Chromosomally Integrated Human Herpesvirus 6: Models of Viral Genome Release from the Telomere and Impacts on Human HealthSemantic proximity Read ↗

Dual roles for the telomeric repeats in chromosomally integrated human herpesvirus-6Semantic proximity Read ↗

The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitroSemantic proximity Read ↗

Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosomeSemantic proximity Read ↗

Unbiased optical mapping of telomere-integrated endogenous human herpesvirus 6Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.