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CHRONIC PANCREATITIS IN A PATIENT WITH THE p.Asn34Ser HOMOZYGOUS SPINK1 MUTATION--OWN EXPERIENCE.

Developmental period medicine - 1 Jan 2000

Rygiel Agnieszka Magdalena, Wojnicka-Stolarz Małgorzata, Niepokój Katarzyna, Oracz Grzegorz, Bal Jerzy, Wertheim-Tysarowska Katarzyna, Gutkowski Krzysztof

Abstract excerpt

Chronic pancreatitis (CP) is characterized by progressive damage to the exocrine and endocrine cell structures and pancreatic ducts with subsequent fibrosis of the organ. Patients with no apparent etiological factor are classified as having idiopathic CP (ICP). Genetic studies indicate the importance of mutations in the serine protease inhibitor, Kazal type 1 gene (SPINK1) in the pathogenesis of CP This report...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26958679

Genes

SPINK1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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