Article
Contribution of ENPP1, TCF7L2, and FTO polymorphisms to type 2 diabetes in mixed ancestry ethnic population of South Africa.
African health sciences - 1 Dec 2015
Yako Yandiswa Y, Madubedube Jabulisile H, Kengne Andre P, Erasmus Rajiv T, Pillay Tahir S, Matsha Tandi E
Abstract excerpt
BACKGROUND: Transcription factor 7-like 2 gene (TCF7L2), fat mass and obesity-associated gene (FTO), and ectonucleotide pyrophosphatase/phosphodiesterase gene (ENPP1) are known risk loci for type 2 diabetes (T2DM) mostly in European populations. OBJECTIVES: To assess the association of these genes with T2DM risk in a South African mixed-ancestry population. METHODS: Five hundred and sixty six participants were...
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