Article
Estrogen receptor-alpha as a predictive biomarker in endometrioid endometrial cancer.
Gynecologic oncology - 1 May 2016
Backes Floor J, Walker Christopher J, Goodfellow Paul J, Hade Erinn M, Agarwal Garima, Mutch David, Cohn David E, Suarez Adrian A
Abstract excerpt
BACKGROUND: We sought to validate the prognostic significance of estrogen receptor alpha (ERα) expression and to investigate the relationship between ESR1 mutation status and outcomes in a large cohort of patients with endometrial cancer. We also investigated the predictive value of ERα for lymph node involvement in a large surgically staged cohort. METHODS: A tumor microarray (TMA) was constructed including only...
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