Article
A novel Markov Blanket-based repeated-fishing strategy for capturing phenotype-related biomarkers in big omics data.
BMC genetics - 9 Mar 2016
Li Hongkai, Yuan Zhongshang, Ji Jiadong, Xu Jing, Zhang Tao, Zhang Xiaoshuai, Xue Fuzhong
Abstract excerpt
BACKGROUND: We propose a novel Markov Blanket-based repeated-fishing strategy (MBRFS) in attempt to increase the power of existing Markov Blanket method (DASSO-MB) and maintain its advantages in omic data analysis. RESULTS: Both simulation and real data analysis were conducted to assess its performances by comparing with other methods including χ(2) test with Bonferroni and B-H adjustment, least absolute...
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