Article
[Clinicopathologic features of succinate dehydrogenase-deficient gastrointestinal stromal tumor].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Mar 2016
Cheng Yuanhua, Zhang Zhongfeng, Zhu Hefen, Guo Lixin, Cheng Yuandong
Abstract excerpt
OBJECTIVE: To investigate clinicopathologic features of succinate dehydrogenase-deficient gastrointestinal stromal tumors (SDH-deficient GIST). METHODS: Immunohistochemical EnVision technique was used to assess the expression of succinate dehydrogenase subunit B (SDHB) in 192 cases of GIST. Cases of SDH-deficient GIST were further evaluated for the presence of CKIT exons 9, 11, 13 and 17 mutations and PDGFRA...
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