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Article

[Wild-type gastroinestinal stromal tumors].

Bulletin du cancer - 1 Apr 2020

Djerouni Mohamed, Dumont Sarah N

Abstract excerpt

Gastrointestinal stromal tumors (GIST) are the most common non-epithelial tumors of the gastrointestinal tract. Wild-type GISTs (WT-GIST) consist of a rare heterogeneous group characterized by the lack of activating mutations in the tyrosine kinase receptor (Kit) and/or platelet derived growth factor receptor A (PDGFRA). However, WT-GIST is characterized by other genomic alterations, including dehydrogenase...

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PMID: 32063345
DOI: 10.1016/j.bulcan.2019.12.007

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