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Article

Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals.

eLife - 8 Mar 2016

Diehl William E, Patel Nirali, Halm Kate, Johnson Welkin E

Abstract excerpt

Mammalian genomes typically contain hundreds of thousands of endogenous retroviruses (ERVs), derived from ancient retroviral infections. Using this molecular 'fossil' record, we reconstructed the natural history of a specific retrovirus lineage (ERV-Fc) that disseminated widely between ~33 and ~15 million years ago, corresponding to the Oligocene and early Miocene epochs. Intercontinental viral spread, numerous...

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Identifiers

PMID: 26952212
DOI: 10.7554/eLife.12704
PMCID: PMC4798954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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