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Comparative analysis reveals the long-term coevolutionary history of parvoviruses and vertebrates

29 Nov 2022

Abstract excerpt

Parvoviruses (family Parvoviridae) are small DNA viruses that cause numerous diseases of medical, veterinary, and agricultural significance and have important applications in gene and anticancer therapy. DNA sequences derived from ancient parvoviruses are common in animal genomes and analysis of these endogenous parvoviral elements (EPVs) has demonstrated that the family, which includes twelve vertebrate-specific...

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PMID: 36445931
DOI: 10.1371/journal.pbio.3001867

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