Article
Improved integration time estimation of endogenous retroviruses with phylogenetic data.
PloS one - 4 Mar 2011
Martins Hugo, Villesen Palle
Abstract excerpt
BACKGROUND: Endogenous retroviruses (ERVs) are genetic fossils of ancient retroviral integrations that remain in the genome of many organisms. Most loci are rendered non-functional by mutations, but several intact retroviral genes are known in mammalian genomes. Some have been adopted by the host species, while the beneficial roles of others remain unclear. Besides the obvious possible immunogenic impact from...
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