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Article

Signature of viral fossils: a comparative genomics approach to understand the diversity of endogenous retroviruses in bats.

Virus research - 1 Dec 2024

Lamba Vinita, Herlekar Ipsita, Chatterjee Durbadal, Patel Kirnalee, Garg Kritika M, Chattopadhyay Balaji

Abstract excerpt

Endogenous retroviruses (ERVs) are traces of past viral infections commonly found in vertebrate genomes. Many ERVs are tightly regulated by the host genomes and co-opted for various functions within the hosts. Bats are the only true volant mammals, with the smallest mammalian genomes and a high fraction of ERVs within the genomes. They are important hosts for various zoonotic viral pathogens and can effectively...

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Identifiers

PMID: 39419354
DOI: 10.1016/j.virusres.2024.199484
PMCID: PMC11546543

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