Article
No evidence of increased breast cancer risk for proven noncarriers from BRCA1 and BRCA2 families.
Familial cancer - 1 Oct 2016
Nielsen Henriette Roed, Petersen Janne, Krogh Lotte, Nilbert Mef, Skytte Anne-Bine
Abstract excerpt
In families screened for mutations in the BRCA1 or BRCA2 genes and found to have a segregating mutation the breast cancer risk for women shown not to carry the family-specific mutation might be at above "average" risk. We assessed the risk of breast cancer in a clinic based cohort of 725 female proven noncarriers in 239 BRCA1 and BRCA2 families compared with birth-matched controls from the Danish Civil...
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