Article
In depth analysis of the mechanism of action of metal-dependent sigma factors: characterization of CorE2 from Myxococcus xanthus.
Nucleic acids research - 8 Jul 2016
Marcos-Torres Francisco Javier, Pérez Juana, Gómez-Santos Nuria, Moraleda-Muñoz Aurelio, Muñoz-Dorado José
Abstract excerpt
Extracytoplasmic function sigma factors represent the third pillar of signal-transduction mechanisms in bacteria. The variety of stimuli they recognize and mechanisms of action they use have allowed their classification into more than 50 groups. We have characterized CorE2 from Myxococcus xanthus, which belongs to group ECF44 and upregulates the expression of two genes when it is activated by cadmium and zinc....
Topics
- Bacterial Proteins
- Cadmium
- Copper
- Cysteine
- Gene Expression Regulation, Bacterial
- Mutation
- Myxococcus xanthus
- Promoter Regions, Genetic
- Sigma Factor
- Trans-Activators
- Transcription, Genetic
- Zinc