Mutational analysis of the Myxococcus xanthus Omega4406 promoter region reveals an upstream negative regulatory element that mediates C-signal dependence.

Abstract excerpt

C signaling plays a key role in coordinating cell movement and differentiation during the multicellular developmental process of Myxococcus xanthus. C signaling regulates expression of genes induced after about 6 h into development, when cells are forming mounds. One gene whose expression depends absolutely on C signaling was identified by insertion of a transposable element at site Omega4406 which generated a...

Topics

• Bacterial Proteins
• Cell Division
• Mutation
• Myxococcus xanthus
• Promoter Regions, Genetic
• Protamine Kinase
• Signal Transduction
• Transcription Factors