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Article

Association of a variable number tandem repeat in the NLRP3 gene in women with susceptibility to RVVC.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 May 2016

Jaeger M, Carvalho A, Cunha C, Plantinga T S, van de Veerdonk F, Puccetti M, Galosi C, Joosten L A B, Dupont B, Kullberg B J, Sobel J D, Romani L, Netea M G

Abstract excerpt

Vaginal infections with Candida spp. frequently occur in women of childbearing age. A small proportion of these women experience recurrent vulvovaginal candidosis (RVVC), which is characterized by at least three episodes of infection in one year. In addition to known risk factors such as antibiotics, diabetes, or pregnancy, host genetic variation and inflammatory pathways such as the IL-1/Th17 axis have been...

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Identifiers

PMID: 26951262
DOI: 10.1007/s10096-016-2600-5
PMCID: PMC4840230

Genes

NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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