Article
Frequency of interleukin-4 (IL-4) -589 gene polymorphism and vaginal concentrations of IL-4, nitric oxide, and mannose-binding lectin in women with recurrent vulvovaginal candidiasis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 May 2005
Babula Oksana, Lazdāne Gunta, Kroica Juta, Linhares Iara M, Ledger William J, Witkin Steven S
Abstract excerpt
BACKGROUND: A C-->T substitution at position -589 in the interleukin-4 (IL-4) gene is associated with increased production of IL-4. Associations between this polymorphism and recurrent vulvovaginal candidiasis (RVVC), as well as vaginal concentrations of IL-4 and the anticandidal compounds nitric oxide (NO) and mannose binding lectin (MBL), were evaluated. METHODS: Vaginal samples obtained by lavage from 42 women...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.