Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Understanding Vascular Diseases: Lessons From Premature Aging Syndromes.

The Canadian journal of cardiology - 1 May 2016

Ikeda Yuichi, Kumagai Hidetoshi, Motozawa Yoshihiro, Suzuki Jun-Ichi, Akazawa Hiroshi, Komuro Issei

Abstract excerpt

Early human mummies examined recently by computed tomography demonstrated a high prevalence of vascular calcification, a pathognomonic sign of atherosclerosis, which was correlated with estimated age at death. Early populations had little exposure to modern-day metabolic risk factors: these observations thus suggest that humans have an inherent age-dependent predisposition to atherosclerosis. Premature aging...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Aging, Premature
Share to Atherosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lamin Type A

Share to Mutation

Share to Phenotype

Share to Progeria

Share to Werner Syndrome

Source

Identifiers

PMID: 26948039
DOI: 10.1016/j.cjca.2015.12.003

Genes

WRN
LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Understanding Vascular Diseases: Lessons From Premature Aging Syndromes.PMID 26948039Read ↗

Accelerated aging syndromes, are they relevant to normal human aging?Semantic proximity Read ↗

Hutchinson-Gilford Progeria Syndrome: A Premature Aging Disease.Semantic proximity Read ↗

Premature aging syndromes: From patients to mechanism.Semantic proximity Read ↗

Premature aging disorders: A clinical and genetic compendium.Semantic proximity Read ↗

Molecular insights into the premature aging disease progeria.Semantic proximity Read ↗

Towards delineating the chain of events that cause premature senescence in the accelerated aging syndrome Hutchinson-Gilford progeria (HGPS).Semantic proximity Read ↗

Vascular senescence in progeria: role of endothelial dysfunctionSemantic proximity Read ↗

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.Semantic proximity Read ↗

Unraveling the mysteries of Hutchinson-Gilford progeria syndrome: a comprehensive review of LMNA gene mutations.Semantic proximity Read ↗

Molecular and Cellular Mechanisms Driving Cardiovascular Disease in Hutchinson-Gilford Progeria Syndrome: Lessons Learned from Animal Models.Semantic proximity Read ↗

Search and insights into novel genetic alterations leading to classical and atypical Werner syndrome.Semantic proximity Read ↗

Metabolic Dysfunction in Hutchinson–Gilford Progeria SyndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.