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Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq

8 Jun 2020

Abstract excerpt

BACKGROUND: Plasmodium parasites undergo several major developmental transitions during their complex lifecycle, which are enabled by precisely ordered gene expression programs. Transcriptomes from the 48-h blood stages of the major human malaria parasite Plasmodium falciparum have been described using cDNA microarrays and RNA-seq, but these assays have not always performed well within non-coding regions, where...

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PMID: 32513207
DOI: 10.1186/s12864-020-06787-5

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