Article
Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation
2019-11-25
Abstract excerpt
<title>Abstract</title> <p>Background: Malaria pathogenesis relies on sexual gametocyte forms of the malaria parasite to be transmitted between the infected human and the mosquito host but the molecular mechanisms controlling gametocytogenesis remains poorly understood. Here we provide a high-resolution transcriptome of Plasmodium falciparum as it commits to and develops through gametocytogenesis. Results : The g...
Topics
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- Complement system in diseases
- Evolution and Genetic Dynamics
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Invertebrate Immune Response Mechanisms
- Malaria Research and Control
- Neurobiology and Insect Physiology Research
- Sperm and Testicular Function
- Trypanosoma species research and implications
Identifiers and source
- Literature Corpus work
- 6b0ee20c-ba28-5d0d-ac78-f52745278595
- DOI
- 10.21203/rs.2.12867/v3